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This Application was produced after careful consideration of the scientific and medical knowledge and the evidence available at the time of publication. The results and recommendations provided by this application are not intended to, and should not, replace clinical judgment of the care provider. Further, the material is not intended to present the only, or necessarily the best, methods of procedures for the medical situation, but rather is intended to represent an approach, view, statement, or opinion. The content in this product is presented as an educational service intended for licensed healthcare professionals. Therapeutic options should be determined after discussion between the patient and their care provider.
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© The American College of Cardiology Foundation 2017
All Rights Reserved. The content of this app has been published for personal and educational use only. No commercial use is authorized.
The ACC LDL-C Manager app is meant to be used in relation to patients who may need medical treatment to lower their LDL-C, particularly with the goal to lower their risk for heart disease and stroke.
The ACC LDL-C Manager app contains three tools to help clinicians manage a patient’s LDL-C from therapy initiation through treatment calibration with a goal of lowering ASCVD risk:
While some clinicians may already be familiar with the ASCVD Risk Estimator and Statin Intolerance tools, the LDL-C Lowering Therapy tool is a brand new addition to ACC’s family of mobile tools related to this topic. Each tool within the app is designed to be used on its own or in combination to manage a patient’s therapy throughout their continuum of care. The LDL-C Manager App hopes to streamline use at point of care by offering access to all of ACC’s LDL-C management tools from one place.
The ASCVD Risk Estimator within this app offers the same functionality as ACC’s pre-existing app of the same name. It is intended as a companion tool to the 2013 ACC/AHA Guideline on the Assessment of Cardiovascular Risk and the 2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults. This Risk Estimator enables health care providers and patients to estimate 10-year and lifetime risks for atherosclerotic cardiovascular disease (ASCVD), defined as coronary death or nonfatal myocardial infarction, or fatal or nonfatal stroke, based on the Pooled Cohort Equations and lifetime risk prediction tools. The Risk Estimator is intended for use with patients without ASCVD with a LDL-cholesterol <190 mg/dL.
Advice from the LDL-C Lowering Therapy tool is derived from the 2016 ACC Expert Consensus Decision Pathway on the Role of Non-Statin Therapies for LDL-Cholesterol Lowering in the Management of Atherosclerotic Cardiovascular Disease Risk, meant to address current gaps in care for LDL-C lowering by providing firmer and more specific guidance on the adequacy of statin therapy and whether or when to use non-statin therapies if response to statins is deemed inadequate. The app is intended for use with patients who are currently taking or who have attempted to take a statin.
The ACC Statin Intolerance App guides clinicians through the process of managing and treating patients who report muscle symptoms while on statin therapy. The information and recommendations in this app are derived from the 2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults, and the prescribing information for each statin.
The information and recommendations in this App and all its component tools are meant to support clinical decision making. They are not meant to represent the only or best course of care, or replace clinical judgment. Therapeutic options should be determined after discussion between the patient and their care provider.
Tools within the app were designed and vetted through collaboration with writing committee members from each of the ACC clinical policy source documents, members of the LDL Think Tank Work Group, and the ACC Best Practices and Quality Improvement Subcommittee. It was further refined via user testing with physicians, nurse practitioners, pharmacists, and other specialties.
This was developed as part of the ACC's Lipid Management Solutions Initiative. Financial support for the Initiative was provided by Amgen Inc. All of the content was independently developed with no sponsor involvement.
Please see the Resources section of this App for links to additional references.
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